Auditory P300 event related potential in the ischemic stroke
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2018-09-19Аутори
Станојевић, Зорица
Метаподаци
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Stroke is often associated with cognitive decline u'hich ma1-
recover-vand rehatrilitation. T'he accepted "gold srandard" fc
cognitive abncirn'ralig'after stroke is a hatlery ol neurcpsrchologicalt
various domains.T'{europs,rtcholcgica} testing ciependson lhe r-rrt
patient and is cften ccmp{ex anel lilne-cunsumilg. so a
neurophysiclogicalmetll*c{ suc}r as ttrre*.r'ert related pctentials I
interesting. The P300 conrscnent r:f tile auditory el'ent rElsted
representinga brain activitv associatedlr'iih vai'iouscognitive
setrectivea.ttention.rnemor]'":*r cieeisionmaking" 'fhe airn of this
clarifv' the effects of ischemie str*ke r:n the amplit*cie and latencl' of
wnve and to correiatcth.eirchanceswith the h4ini Mental StateEramrnati
over a one-vearfoilow-*p peri*d. T'hestudy included60 patients*ith a
everbrain infarction(meanage 57'1*5'2 years,range45-17l'ears)'\\e
the P300 w-aveusing an auditory oddball paradigmin i:aseiine.6 and lf
after infarction. Responseswere recordedfrom f,rontai(Fz) vertex (Czt an,l
(Pz) midline electrode sites with a biauricular refbrence, according
international 10-20 standard. In the stroke patients F300 latenc:' contl
decreasedaver the cbservationperiod with a significantdifferenceafter 6
comparedto baseline(p<0.05)andafter 12monthseomparedto baseline(
The amplitude F30C) shos,ed no significant changes over time. Statisti
significantnegativecoryelationtretweenF300 latenciesand h,'{MSEscores
bas'eXine atPzsite(r:-0.339,p<0"01),after3 months(r:-0'59,p<0'01)andafter
months(r:-0.35.p<0.01)afterthestroke. Our stuclyemphasiees theimportanc.c
P3CI0latene-v- in the detectionand follow-up of cognitive changesafter isc
stroke.
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