| dc.contributor.author | Ćirić S., Slavica Ć., Danijela P., Zvonko S., Zoran I., Božidar M. Prodanović D., Spasić Z., Ilić Z., Milošević B., | |
| dc.date.accessioned | 2022-09-14T06:52:24Z | |
| dc.date.available | 2022-09-14T06:52:24Z | |
| dc.identifier.citation | 31001 Еколошки приступ и увођење савремених биотехнологија као основа унапређења технологије производње гајених преживара Министарство просвете науке и технолошког развоја Републике Србије | en_US |
| dc.identifier.uri | https://platon.pr.ac.rs/handle/123456789/437 | |
| dc.description.abstract | The main objectives of this work were to determine the prevalence of
ESBL-producing E. coli and to establish antimicrobial susceptibility pattern of
ESBL-producing and non producing strains. The tests were carried out in the
laboratory of military hospital, Military Medical Academy (MMA), Belgrade,
Serbia, during the second half of 2017 (July-December). Four hundred and
fifty-one E. coli strains isolated from various clinical specimens were tested.
Detection of ESBLs isolates was carried out by the double-disc synergy test
and confirmed by double-disc diffusion test. The overall incidence of ESBLs
production among E. coli isolates was 34%. The highest frequency of ESBLs
production was noted in blood isolates (82%), which was statistically significant
(p < 0.05) compared to the other isolates. The highest susceptibility of E. coli
strains was expressed to imipenem (100%) and to amikacin (88%), so these
antibiotics can be considered antibiotics of choice in the treatment of infections
caused by this bacterium. The isolates that produced ESBLs were significantly
(p < 0.05) more resistant to the classes of antibiotics other than beta-lactams
compared to the non-ESBL-producers. These results show very high frequency
of ESBLs production in the tested isolates and suggest the urgent introduction
of some measures in clinical practice, such as quicker and reliable diagnostic
tools, new effective therapies and reasonable use of existing drugs | en_US |
| dc.language.iso | en_US | en_US |
| dc.title | ANTIBIOTIC RESISTANCE AND EXTENDED SPECTRUM BETA-LACTAMASES (ESBLs) PRODUCTION IN ESCHERICHIA COLI STRAINS ISOLATED FROM INTRAHOSPITAL PATIENTS | en_US |
| dc.type | clanak-u-casopisu | en_US |
| dc.description.version | publishedVersion | en_US |
| dc.identifier.doi | doi.org/10.7546/CRABS.2020.01.14 | |
| dc.subject.keywords | antibiotic resistance, Escherichia coli, extended spectrum beta-lactamases, intrahospital patients | en_US |
| dc.type.mCategory | M23 | en_US |
| dc.type.mCategory | openAccess | en_US |
| dc.type.mCategory | M23 | en_US |
| dc.type.mCategory | openAccess | en_US |
