| dc.contributor.author | Ćirić S., S. S. Ćirić, D. I. Stanišić, B. N. Milošević, Z. Ž. Ilić, Z. Lj. Spasić Stanišić D., Milošević B., Ilić Z., Spasić Z. | |
| dc.date.accessioned | 2022-09-13T12:14:05Z | |
| dc.date.available | 2022-09-13T12:14:05Z | |
| dc.identifier.citation | 31001 Еколошки приступ и увођење савремених биотехнологија као основа унапређења технологије производње гајених преживара Министарство просвете науке и технолошког развоја Републике Србије | en_US |
| dc.identifier.uri | https://platon.pr.ac.rs/handle/123456789/434 | |
| dc.description.abstract | The aim of this study was to determine the prevalence
of extended spectrum beta-lactamases (ESBLs) production in hospital strains of Enterobacteriaceae isolated
from various clinical specimens (urine, blood and
wound swabs) from hospitalized patients at the Military
Medical Academy, Belgrade, Serbia. During six months
of study, a total of 1034 isolates of Enterobacteriaceae
were tested for antimicrobial susceptibility and screened
for ESBL production according to standard methods.
The overall prevalence of ESBL production in the hospital isolates of Enterobacteriaceae was 57.4%. Among
the isolates, minimum frequency of resistance was found
for amikacin (25.2%), and maximum for ampicillin
(84.5%). The strain resistant to imipenem could not be
isolated. Resistance to the tested antibiotics was higher in ESBL producers than non-producers (P < 0.05).
Among Escherichia coli isolates, the prevalence of
ESBL production was less than 50% (33.9%). ESBLs
were most often produced by isolates of Serratia spp.
(85.2%) and Klebsiella spp. (81.8%). Blood specimens
were the most common sources of ESBL-producing
isolates (84.0%). These findings might help clinicians
in deciding the appropriate empirical treatment for
intrahospital patients and emphasize the increasing
problem of antimicrobial resistance in Serbia | en_US |
| dc.language.iso | en_US | en_US |
| dc.title | Prevalence of extended spectrum beta-lactamases among Enterobacteriaceae isolated from intrahospital patients in Serbia | en_US |
| dc.type | clanak-u-casopisu | en_US |
| dc.description.version | publishedVersion | en_US |
| dc.identifier.doi | doi: 10.18520/cs/v115/i11/2071-2078 | |
| dc.subject.keywords | Antibiotic resistance and susceptibility, Enterobacteriaceae, extended spectrum beta-lactamases, human isolates. | en_US |
| dc.type.mCategory | M22 | en_US |
| dc.type.mCategory | openAccess | en_US |
| dc.type.mCategory | M22 | en_US |
| dc.type.mCategory | openAccess | en_US |
