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dc.contributor.authorKrstić, Milena
dc.contributor.authorPetković, Branka
dc.contributor.authorMilčić, Miloš
dc.contributor.authorMišić, Dušan
dc.contributor.authorSantibanez, Juan Francisco
dc.date.accessioned2023-04-11T10:42:36Z
dc.date.available2023-04-11T10:42:36Z
dc.identifier.citationMinistry of Science and Technological Devel-opment of the Republic of Serbia, Project No. OI 172014en_US
dc.identifier.citationMinistry of Science and Technological Devel-opment of the Republic of Serbia, Project No. III 45022en_US
dc.identifier.citationMinistry of Science and Technological Devel-opment of the Republic of Serbia, Project No. OI 175053en_US
dc.identifier.urihttps://platon.pr.ac.rs/handle/123456789/1190
dc.description.abstractTwo new nitrato complexes of zinc and nickel with 1,4,8,11-tetrakis(2-pyridylmethyl)-1,4,8,11-tetraazacyclotetradecane (tpmc), have been synthesized and characterized. The IR spectral peaks showed that the coordinated and ionic nitrate ions are in agreement with the formula proposed by elemental anal-ysis. Conductometric titrations predicted methanol to be a convenient solvent for synthesis and revealed the stoichiometry of the complexes, while molar electrical conductivities indicated a 1 : 3 complex elec-trolyte type for the zinc complex, and a 1 : 2 complex electrolyte type for the nickel complex. The opti-mized complex structure was obtained by molecular modeling and density functional theory calculations. The biological activity of the novel complexes was examined by screening eight different bacterial strains and two cancer cell lines. The zinc complex showed better antimicrobial activity against the bacterial strains, while the complexes did not show significance antiproliferative activity toward cancer cells MCF-7 and MDA-MB-231.en_US
dc.language.isoen_USen_US
dc.titleSynthesis, characterization and biological study of new dinuclear zinc(II) and nickel(II) octaaza macrocyclic complexesen_US
dc.title.alternativeMacedonian Journal of Chemistry and Chemical Engineeringen_US
dc.typeclanak-u-casopisuen_US
dc.description.versionpublishedVersionen_US
dc.identifier.doihttps://doi.org/10.20450/mjcce.2019.1599
dc.citation.volume38
dc.citation.issue1
dc.citation.spage1
dc.citation.epage11
dc.subject.keywordszincen_US
dc.subject.keywordsnickelen_US
dc.subject.keywordstpmcen_US
dc.subject.keywordscomplexen_US
dc.subject.keywordsbiological activityen_US
dc.type.mCategoryM23en_US
dc.type.mCategoryclosedAccessen_US
dc.type.mCategoryM23en_US
dc.type.mCategoryclosedAccessen_US


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