Dinuklearni kompleksi srebra(I) sa N,N',N'',N'''-tetrakis(2-piridilmetil)-1,4,8,11-tetraazaciklotetradekanom: sinteza, karakterizacija i biološka aktivnost

Abstract

U ovom radu, N,N',N'',N'''-tetrakis(2-piridilmetil)-1,4,8,11-tetraazaciklotetradekan (tpmc) kao makrociklicni ligand sa 2-piridilmetil grupama je korišćen za sintezu kompleksa srebra(I). Različite AgX soli (X = CF3SO3-, CF3COO- i BF4-) su korišćene za sintezu u cilju ispitivanja uticaja kontra-anjona na nuklearnost, stabilnost i biološku aktivnost kompleksa. Sintetisani kompleksi srebra(I) su okarakterisani primenom različitih spektroskopskih metoda, ciklične voltametrije i rendgenske strukturne analize. Ovi kompleksi pokazuju značajnu antimikrobnu aktivnost prema različitim sojevima bakterija i gljiva.

In this study, N,N',N'',N'''-tetrakis(2-pyridylmethyl)-1,4,8,11-tetraazacyclotetradecane (tpmc) as a macrocyclic ligand with pendant 2-pyridylmethyl groups was used for the synthesis of silver(I) complexes. Different AgX salts (X = CF3SO3-, CF3COO- and BF4-) were used for the synthesis in order to investigate the influence of a counter-anion on nuclearity, stability and biological activity of the complexes. The synthesized complexes were characterized by different spectroscopic techniques, cyclic voltammetry and single-crystal X-ray diffraction analysis. All investigated complexes show remarkable antimicrobial activity against different bacterial and fungal strains.